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In half a dozen clinical trials, the compound helped 6,000 patients lose up to 10% of their body weight over a year and maintain that loss for another year.
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According to Cochrane review in 2007 Rimonabant "may increase the odds of quitting approximately 1(1/2)-fold" [9] .
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Experts say that potentially 20% of Britain's population could be eligible for treatment with rimonabant.
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HbA1c and HDL-cholesterol levels were independent of the weight loss achieved, indicating a direct effect of rimonabant on these parameters, say authors.
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